Vol. 13 No. 1 (2024): Chettinad Health City Medical Journal

Editorial

Diabesity: A Modern Health Crisis and the Need for Integrated Care

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  • March 30th 2024
  • Raja D
Abstract

Diabesity, a term that captures the dual epidemic of diabetes and obesity, represents one of the most pressing health challenges of the 21st century. The convergence of these conditions exacerbates their impacts, leading to severe complications and an increased burden on healthcare systems.1 Addressing diabesity requires an integrated care approach that combines clinical, behavioural, and public health strategies to effectively manage and prevent these intertwined conditions.

Research Article

A Prospective Observational Study on Assessment of Antibiotic Therapy in Renal Failure Patients with Infections

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  • March 30th 2024
  • Pradeep Battula, Somala Savithri, Kamini Poojitha, Y Saivani
Abstract

The combination of renal failure and infections is the primary cause of death. Effective drug treatment is crucial for managing these conditions and reducing illness and death risks.Aim: The study aims to identify the type of microorganism causing kidney or renal infection, its sensitivity patterns and to assess the type of antibiotic prescribed in renal failure patients with infections.

An Analysis of Socio-Demographic and Haematologic Profiles of Platelet Donors at a Tertiary Cancer Centre in South India

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  • March 30th 2024
  • Yalamanchili Swapna
Abstract

Platelets have an active role in haemostasis and are used in patients mainly to stop or prevent life-threatening bleeding. The blood components transfused commonly are packed red blood cells followed by platelets.One of the objectives of the World Health Organization is to promote the availability and safety of blood by targeting blood donors in certain environments.

Anti-Bacterial Activity of Homoeopathic Nosodes Anthracinum, Pyrogenium and Variolinum in 30 C, 200 C and 1 M Potencies Against Methicillin Resistant Staphylococcus Aureus - An In Vitro Study

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  • March 30th 2024
  • Sweetlin Simi P, Bencitha Horrence Mary, Priyashree R, Maalolan S, Rachana Mol RS
Abstract

he homoeopathic system of medicine is still considered as pseudoscience by the scientific community due to the lack of material substance in highly diluted medicinal formulations, despite clinical results. On the other hand, biomedicine is threatened by antimicrobial resistance against various pathogens. Methicillin-Resistant Staphylococcus aureus (MRSA), a virulent strain of the bacteria Staphylococcus aureus, is resistant to several antibiotics like methicillin, nafcillin, oxacillin, and cephalosporins. In this study, homoeopathic nosodes also called biotherapeutic preparations, which are homoeopathic preparations made from pure microbiological cultures isolated from sick tissue and clinical samples like secretions, discharges, etc., were tested against MRSA to understand its antibacterial effects.

Assessment of Musculoskeletal Pain Among Prolonged Motorcycle Riders

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  • March 30th 2024
  • Siddhi Sawant, Namrata Kadam
Abstract

The work-related motorcyclist is extremely prone to driving-related issues due to the duration of riding. They travel to several places within the allotted time every day, which is not only exhausting but also leads to several severe health-related issues which may impact their postural formations. The severity of musculoskeletal problems occurring in motorcyclists may lead to lifelong problems for the individual.

Comparison of Flexural Strength and Colour Stability of Dentures Characterised Using Conventional Auto-Polymerising Resin Stains and New Light-Cured Composite Staining Material: An In Vitro Study

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  • March 30th 2024
  • Naveen Raj S, Vidyashree Nandini V, Surya Rengaswamy, Ananth Prathap
Abstract

Complete dentures are a common treatment option for edentulous patients. They provide masticatory functions as well as aesthetics synchronising with the surrounding oral soft tissue. Aim: To examine and compare the flexural strength and colour stability of heat-activated acrylic resin incorporated with auto-polymerising acrylic stains and light-cured gingival shade composite resin

Cost-Effective Non-Invasive Blood Glucose Monitoring System with Mobile Application for Management of Diabetic Patients

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  • March 30th 2024
  • Amit Kumar Singh, Harini H, Kuralarasi P, Monigha RM, Ravina G, Maya Datt Joshi
Abstract

Diabetes is a significant health concern worldwide. The current methods of monitoring the glucose level include invasive and minimally invasive methods, which cause pain and have some limitations too. We have discussed different methods of blood glucose detection.Aims: The aim of the study is to develop a low-cost, non-invasive device, especially for the rural public, to ensure diabetes management can be done at home.

Development of Nutritive Cereal Bar Incorporating Buckwheat for School-Going Children

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  • March 30th 2024
  • Nikhila Vani Sangathi, Damini Soni
Abstract

The development of low-cost, nutritious, and convenient snacks has become an important aspect of food technology. To meet the increasing market needs, formulation strategies of nutritive bars are evolving with each passing day and are changing daily to match the growing market demands. The main objective of the current study was to create a new formulation of cereal bars using flour of buckwheat, green gram whole, almonds, jaggery, white chocolate, and gum acacia (as a binding agent).

Effect of Integrated Physiotherapy Protocol on Functional Performance and Mental Health Among Subjects with Osteoarthritis Knee

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  • March 30th 2024
  • Rabia Aziz, Habiba Sundus, Sohrab A Khan, Jawed Firdaus, Ashfaque Khan , Charu Chhabra
Abstract

Osteoarthritis (OA) is the most prevalent musculoskeletal condition characterised by asymmetric joint space narrowing, osteophyte development, and articular cartilage degradation resulting in severe discomfort and incapacity with financial, social, and personal impact. Patients diagnosed with osteoarthritis at the knee joint experience psychological co-morbidities such as anxiety and depression.

Effectiveness of Hoffman’s Exercise on Breastfeeding Among Postnatal Mothers with Flat or Inverted Nipple in Tertiary Care Hospital, Puducherry

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  • March 30th 2024
  • Preethi B, Annie Annal M, Lavanya S, Poongodi V, Umamaheswari R
Abstract

The ideal balanced diet for infants up to six months of age is breast milk. Breastfeeding depends upon the baby’s attachment with correct positioning to the mother’s breast, whereas the most common abnormalities of the nipple such as a flat and inverted nipple might be a barrier to breastfeeding. Hoffman’s exercise is a method for handling these issues.

Effectiveness of Twenty Minutes Walk Training With and Without High-Intensity Interval Training (HIIT) on Cardiovascular Endurance Among Healthy Individuals - A Randomised Controlled Trial

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  • March 30th 2024
  • Abinaya S, Muralisankar KSI, Dhivyadharshini V, Santhiya S
Abstract

Body, mind, and emotions change as we age, and signs include hair loss, hair greying, elasticity loss in the skin, weight gain, and decreases in physical strength and endurance. In the third and fourth decade of life, maximum aerobic capacity (maximum volume of O2) declines gradually from 3% to 6% in adults who live in communities. The ability of the cardiovascular system to transport and use oxygen is influenced by both central and peripheral factors. Of the central parameters influencing endurance performance, cardiac output shows the greatest ageing-related reductions. This study evaluates healthy individuals’ cardiovascular endurance using 20-minute walk training with and without high-intensity interval training.

Efficacy of Honey and Local Anaesthetics as Tissue Fixatives

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  • March 30th 2024
  • Malavika, Jebisha, Mahalingam Bhuvaneswari, Sathish Muthukumar, Sreeja, Harini Priya A H
Abstract

Fixatives are crucial in the preparation of tissue for pathological diagnosis. The gold standard for tissue specimen fixation is formalin. Since formalin is costly, carcinogenic, and difficult to get, there is interest in finding a viable replacement. In addition to being a dehydrator, honey also contains antibacterial and antioxidant qualities. The risks associated with local anaesthetics (LA), which are accessible in any clinic, are negligible. The purpose of this study was to evaluate the efficacy of using honey and a local anaesthetic solution in place of formalin as a fixative for tissue processing.

Extracellular Enzymatic Activity of Malassezia spp. Isolated from Pityriasis Versicolor Patients and Healthy Individuals

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  • March 30th 2024
  • Vignesh Kanna Balaji, Latha Ragunathan, Kavitha Kanniyan, Jeyakumari Duraipandian
Abstract

Malassezia spp. is incapable of synthesising fatty acids. It takes external lipids as a nutritional source for survival by secreting various lipase enzymes, which degrade sebum to produce and uptake fatty acid. During this process, it produces certain extracellular enzymes; lipase, phospholipase, and protease which may act as virulence factors. We intend to determine the extracellular enzymatic action of Malassezia spp. isolated from individuals with pityriasis versicolor and healthy individuals.

Optimising Therapeutic Benefits: Suboccipital Muscle Inhibition Technique for Enhanced Balance and Alleviation of Pain Intensity in Individuals with Chronic Neck Pain

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  • March 30th 2024
  • Madan Kusum, Bharti Sharma, Harsirjan Kaur, Charu Chhabra
Abstract

Chronic neck pain is one of the diseases amongst other reported musculoskeletal diseases prevalent in the population. Suboccipital muscle inhibition is one of the manual techniques used to reduce the myofascial restriction in the muscles of the occiput region, by activation of the autonomic nervous system (parasympathetic system) and raises the amount of endorphins, which lessens the pain sensitivity, and relation of the myodural bridge which connects the rectus capitis posterior minor muscle to dura which affects balance ability.

Selenium and Selenium-Dependent Enzymes in Hypothyroidism

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  • March 30th 2024
  • Ayyappan S, Priya K Dhas
Abstract

Hypothyroidism is a prevalent endocrine disorder characterised by an underactive thyroid gland and reduced production of thyroid hormones. Selenium, an essential trace mineral, plays a critical role in thyroid function and the synthesis of thyroid hormones. Selenium-dependent enzymes, including glutathione peroxidase (GPx) and iodothyronine deiodinases (DIOs) type II, thioredoxin reductase and superoxide dismutase (SOD) are involved in regulating thyroid hormone metabolism and maintaining thyroid gland health. Understanding the significance of selenium and selenium-dependent enzymes in hypothyroidism can provide valuable insights into the disease mechanisms and potential therapeutic interventions.

Review Article

Global Health Partnerships in Contemporary World: An Overview, Orientation and Evolution

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  • March 30th 2024
  • Rose Govindaraj
Abstract

Global health partnerships have become increasingly important in addressing the global burden of disease and improving health outcomes in low- and middle-income countries. However, the factors that contribute to the success or failure of these partnerships are not well understood.

Perspective

Artificial Intelligence in Digital Therapeutics: Exploring the Tangled Web of Legal Issues

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  • March 30th 2024
  • Vidya Menon
Abstract

The increasing penetration of Artificial Intelligence (AI) technologies has transformed the healthcare ecosystem, making it more efficient, accessible and affordable. In recent years, AI-driven technologies have established immense value in the digital diagnosis and treatment process. AI-enabled imaging and digital diagnostic techniques have facilitated early intervention and treatment of critical conditions such as cancer, heart disease, and diabetes. With the ability to quickly learn and analyse large amounts of health data, AI-based techniques have shown tremendous results in delivering more accurate diagnoses, thereby assisting medical professionals in clinical decision-making.1 The COVID-19 pandemic has also accelerated the adoption of AI-powered remote patient monitoring platforms that connect doctors to patients. In the past three years, as many as 308 AI-enabled medical devices have been either cleared or approved by the United States Food and Drug Administration (US FDA) (Figure 1). It has also been estimated that the healthcare market valuation of global AI shall surpass USD 200 billion by 2030 (Figure 2).

Case Study

A Case Study on Epstein-Barr Virus Infection Induced Haemophagocytic Lymphohistiocytosis

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  • March 30th 2024
  • Harshil P Gadhiya, Yash V Radhanpura, Saurabh A Sanja, Kushal Parekh, Bhavik R Jani
Abstract

One of the effects of Epstein-Barr virus (EBV) infection is a condition known as Haemophagocytic Lymphohistiocytosis (HLH). Unrestrained immune system activation, which results in unrestricted cytokine release and macrophage activation, is the cause of the fatal uncommon condition known as HLH. EBV infection can cause systemic lymphadenopathy, cytopenia, and fulminant constitutional symptoms. Here, we have discussed a case of a 69-year-old man with neurological issues who also had HLH caused by EBV and beta cell lymphoma.

Short Communication

A Comparative Study of Combined Aerobic Exercise Versus Walking on Sleep Quality of Individuals with Insomnia

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  • March 30th 2024
  • Mohamed Nainar A, Hari Babu L, Mohamed Zerein Fathima M, Alagappan Thiyagarajan, C Ramesh, KC Gayathri
Abstract

Insomnia is a disorder which is caused by stress, anxiety, inadequate sleep practices, physical illnesses, mental health conditions, medication usage, and neurological abnormalities which reduce the duration of sleep and lead to difficulties in both initiating sleep and achieving restorative rest. The objective of the study was to evaluate the efficacy of combined aerobic exercise and walking on subjects suffering from insomnia. Thirty participants were selected by simple random sampling method and were divided into the following two groups: Group A (experimental group) consisting of 15 subjects who received combined aerobic exercises (static cycling, jogging, and Zumba dance - 15 minutes each), and Group B (control group) which consisted of 15 subjects who performed only walking for 45 minutes. Pre-test and post-test scores were recorded using the Insomnia Severity Index Scale and Pittsburgh Sleep Quality Index respectively. Statistics were analysed using paired t test and SPSS software. The experimental group and control group showed an increase in sleep hours and quality of life but there was a significantly higher increase in the experimental group in sleep hours as compared to the control group. Hence, this study concluded that combined aerobic exercises proved to be statistically significant in reducing the symptoms of insomnia as compared to walking.

Morphological Changes and Gender-Based Differences in Human Dry Mandible

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  • March 30th 2024
  • Madhu Deva S, Kowsheka V, Vennila G
Abstract

The natural ageing process can cause changes in the teeth and gums, which can further impact the structure and function of the mandible. The major parts of a mandible are the condylar process, the angle of the mandible, and the mandibular canal. These anatomical structures play a key role in various branches of dentistry like orthodontics, prosthodontics, forensic dentistry, and maxillofacial surgery.