The ever growing applications of nanotechnology in medicine prompted the Chettinad Health Chettinad Health City Medical Journal to bring out special issue on nanotechnology in medicine. The overwhelming response from the authors had resulted in many interesting articles covering the wide spectrum of biomedical nanotechnology. I am glad to know that the editorial board of Chettinad Health City Medical Journal has extended the scope by deciding to bring out another issue on the theme of nanotechnology in medicine.

Electrochemical analyses are now very commonly used in many analytical applications. Objectives: Here, the copper electrode is modified by coating Prussian Blue (PB) with the help of self-assembled monolayer (SAM) as an intermediate layer.

Synthesis of silver (Ag) nanoparticles (NPs) from lactic acid bacteria is an alternative and eco-friendly way than many chemical and physical methods.

Plant mediated biosynthesis of metallic nanoparticles is gaining importance due to its simplicity, accuracy, cost-effectiveness and eco-friendliness.

The application of zinc oxide (ZnO) nanoparticles in the field of photocatalysis, ultraviolet (UV) light attenuation as well as in cosmetics and paints has become popular in recent times. Although, ZnO is known to exert oxidative stress by production of reactive oxygen species (ROS) and can also cause cell killing at high doses.

To perform and Analyze Somatosensory Evoked Potentials (SSEP) in Lateral Femoral Cutaneous Nerve of Thigh (LFCN) and to estimate its diagnostic efficacy in detecting Meralgia Paresthetica .

The novel coronavirus disease (COVID-19) which originated from china in December 2019 has infected millions and has caused countless deaths. The main mode of spread is through droplets. The infection mostly causes mild symptoms like fever, cough, sore throat, myalgia etc, but can also cause potentially fatal pneumonia renal failure etc. RT-PCR is currently the best diagnostic test. Since there is no specific drug against the virus, the best way to control the disease is through preventing it by taking care of droplet spread, isolation of infected people and contact tracing. The population should avoid unnecessary travel, maintain social distancing, follow protective measures and proper hygiene.

11 year old boy with history of sinusitis on regular treatment, developed headache and altered sensorium for 1 day. MRI brain contrast showed Extensive spheniod sinusitis with Right temporo parietal contrast enhancing subdural collection with thick capsule( Subdural Empyema).

A 25-year-old female underwent Intercostal Drain (ICD) insertion on the left side of the chest two months back, elsewhere, in view of tension pneumothorax. ICD showed persistent air-leak and patient presented for further management. We performed a left-sided open bullectomy with pleurectomy and she had adequate lung expansion within three post-operative days. This is a classical case of vanishing lung syndrome, where giant bullae occupied more than 90% of left hemi-thorax with mediastinal shift. Successfully treated with bullectomy and recovery was uneventful.

This review focusses its attention on biopolymeric drug carriers for oral delivery applications. The review is intended towards upcoming researchers in the area. It provides a detailed introduction to the types of biopolymeric carriers with specific emphasis on chitosan-based and chitosan-coated carriers. The significant advantages and limitations of these carriers have been detailed. Insight into the mechanism of formation of composite hydrogels, chitosan-coated liposomes, and nanoparticles, their oral delivery pathways have been provided. The article also provides an outline of the current trends in oral drug delivery and future prospects.

In the rapidly developing world, it is very much necessary to make use of sensors and analytical devices for various applications. As nanotechnology is grabbing global attention, developing biosensors with the use of nanoparticles (Nps) is one of the trending topics among research communities. Owing to the properties such as high stability, sensitivity and selectivity carbon nano tubes (CNT) is found as one of the promising candidates for the fabrication of biosensors. From various research results, it is clear that both the single walled CNT and multi walled CNT are used as bio-sensing element. In this context, this short review consolidates the working principle, target analytes and other applications of CNT in a detailed manner.

Amphiphilic molecules have ability to self-assemble above their critical aggregation concentration in aqueous solution, transforming a variety of microstructure or nanostructure. The worm like micelles is one of them having peculiar rod-like or thread-like structure with excellent viscoelastic properties and unique rheological responses. The morphologies and characteristics of such nanostructures depend on the molecular structure of amphiphiles or surfactants and related conditions. The present review concentrates on the stimuli responsive rheological control of wormlike micelles and their applications in biomedicines.

Nanotechnology is an interdisciplinary science which is rapidly progressing in the recent past. Nanoparticles (NPs) exhibit unique properties that label them as molecules having potential applications in engineering, medical and environmental research fields. Due to the limitations associated with the conventional methods of nanoparticle synthesis, there is an upsurge in biological means of nanoparticle synthesis. Nature has bestowed with diverse defence mechanisms in bacteria that help them to survive in any extreme environmental conditions. This property has been righteously exploited by the scientists to meet their need with respect to nanoparticle synthesis. Although extensive reports are available on bacteriogenic synthesis of NPs, the underlying mechanism is yet to be explored. Since bacteria can be easily handled and genetically altered, it can serve as a best system to fabricate nanoparticles with desired physiological properties.