Volume - 10, Number - 1, Jan - Mar 2021

Editorial

Natural Products of Therapeutic Potential

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  • January 1st 2021
  • Lakshmi M
Abstract

Natural products constitute the main source of new pharmaceuticals and healthcare products. The use of natural products has been traced to the extraction and development of several drugs from plants as well as from traditionally used folk medicine. Natural products possess enormous structural and chemical diversity that cannot be matched by any synthetic libraries of small molecules and continue to inspire novel discoveries in chemistry, biology and medicine. Together with the recent advances in microbial genomics and metagenomics. Synthetic biology, fundamental understanding of natural product biosynthesis and bioinformatics and analytical technologies, we are surely entering a New Golden Age of natural products drug discovery.

Original Article

Protective Effect of Ethanolic Extract of Lycopodium Clavatum Against Pathogenic Escherichia Coli and Proteus Vulgaris

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  • January 1st 2021
  • Jagadeesan AJ, Bhatia M, Vimala Devi S, Meera M, Madhumala G, Suresh A, Banerjee A, Pathak S
Abstract

This study aimed to assess the antiproliferative and antioxidant activities of Lycopodium clavatum against the pathogenic strains Escherichia coli and Proteus vulgaris.

Pharmacognostical and Phytochemical Studies to Resolve the Identity of Agnimantha, An Ingredient in Dasamoola

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  • January 1st 2021
  • P. Deepalakshmi, N. Jayshree
Abstract

Ayurvedic medicines will be effective only if they are prepared using genuine medicinal herbs. The major drawback, however, is the difficulty in identifying the genuine medicinal herb prescribed by the founders of the system. Their descriptions of medicinal plant are more poetic than scientific and lack precision because the language that was used is not technical. Agnimantha is one such controversial herb in Ayurveda. It is one of the potent drug prescribed singly as well as in various formulation like Dasamoola and Brihat panchamoola, since ancient time. But there is existing controversy regarding this herb. This study deals with resolving this controversy by doing pharmacognostical and phytochemical studies. Pharmacognostical studies includes morphology, microscopical analysis and proximate analysis. Phytochemical studies includes qualitative evaluation of phytochemicals. Results of this study will be helpful in identifying genuine source. But from all these analysis it is difficult to conclude which is authentic Agnimantha and which can be used as substitute. Hence need further analysis to resolve this existing controversy.

Anti - Inflammatory and Antimicrobial Activity of Protein Isolated from Spirulina Fusiformis

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  • January 1st 2021
  • V. Janani Priya, V. Gomathi, Kumar Ebenezar
Abstract

Inflammation is a pathologic condition that includes a variety of diseases including infectious diseases as they can form on the surface and persist after treatment with diverse antibacterial agents. The natural products have demonstrated their effectiveness in many fields and plant based drugs were also used for human diseases. In this study, the protein from green seaweed (S. fusiformis) was extracted, purified using gel chromatography and the active fractions were identified by using UV-spectroscopy, pooled, dialyzed and quantified. Enriched protein from green seaweed was extracted and mineral components were determined using Atomic absorption spectroscopy (AAS).

Expert Article

Expert Opinion on Plant-Based Medicines

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  • January 1st 2021
  • Anisur Rahman Khuda-Bukhsh
Abstract

Ever since the dawn of human civilization, plants occupy a pivotal position in human life. Various parts of plants like roots, shoot, bark, leaves or fruits not only serve as food and spices, but they are also known to provide various medicines for over 5000 years. Plants serve as a major part of folk medicine, Indian Ayurveda, Siddha medicine, traditional Chinese medicine, Unani, tribal medicine as well as all forms of modern medicine. They play an important role in providing antibiotics, chemotherapy, pain management and halucinogenics.

Review Article

Natural Dietary System and Insulin Resistance

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  • January 1st 2021
  • Santhi Priya S, Kumar Ebenezar K
Abstract

Natural diet or supplements may help fight insulin resistance, a health condition known to raise your risk of type 2 diabetes and heart disease. In people with insulin resistance, the body fails to respond properly to insulin. The body produces more and more insulin to help blood sugar (or "glucose") enters cells, but excess glucose builds up in the bloodstream and, in turn, promotes the onset of diabetes.

Naringenin and its Benecial Effect in Human Healt

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  • January 1st 2021
  • Koyeli Girigoswami, Agnishwar Girigoswami
Abstract

Polyphenols are compounds naturally found in many fruits and vegetables which have been known to exert many health benefits. Among the different types of polyphenols, naringenin is an important polyphenol which has been evidenced to have many health benefits in diseases like cancer, obesity, cardiovascular diseases, diabetes etc. Naringin is the glycosidic form of naringenin which is also useful to protect us from some diseases. The different category of polyphenols and some of the health benefits of naringenin and naringin is discussed in this article.

Biological Routes for the Synthesis of Silver Nanoparticles

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  • January 1st 2021
  • Arthi C, Hikku G S
Abstract

Silver nanoparticles (AgNPs) play a vital role in nano-science and technology field owing to their unique physical and chemical properties such as optical, electrical, thermal, high electrical conductivity, and biological properties. The AgNps are usually synthesized through chemical and biological processes. The major drawback of using chemical techniques is the waste generated during preparation is very high which is toxic, hazardousand causes environmental pollution.T